Associate Scientist II, in vitro Preclinical Development

📋 Description

• Develop and perform cell-based assays to generate data that advance mRNA-tLNP pipeline programs
• Execute in vitro assays to evaluate mRNA-tLNP-mediated T-cell reprogramming, including assessment
• Isolate PBMCs and T cells from leukopaks.
• Use aseptic techniques to culture mammalian cells, including tumor cell lines, T cells, and PBMCs.
• Make stable tumor cell lines using techniques such as electroporation, viral delivery, and
• Perform routine tasks competently and independently, and generate reliable and consistent results.

🎯 Requirements

• Bachelor's Degree, or equivalent education, with typically 3 or more years' experience or Master's
• Previous experience in chimeric antigen receptor (CAR) production and evaluation is desirable.
• Experience with aseptic/sterile techniques culturing of mammalian cells, including cell lines, T
• Experience with viral and non-viral gene transfer techniques to engineer mammalian cells.
• Experience designing and executing assays to assess T cell function including cytotoxicity
• Proficiency in flow cytometry and data processing.

🎁 Benefits

• Paid time off (vacation, holidays, sick)
• Medical/dental/vision insurance
• 401(k) to eligible employees
• Eligible to participate in short-term incentive programs