Director, Nonclinical and Translational Science

📋 Description

• Lead nonclinical and translational studies for assigned programs from candidate nomination through
• Support the clinical teams on first-in-human studies and subsequent clinical development.
• Develop and maintain integrated nonclinical development plans, including pharmacology, toxicology
• Define translational strategies that connect preclinical findings to clinical hypotheses, including
• Serve as immunology subject matter expert on assigned studies and other pipeline programs across
• Provide scientific subject matter expertise in nonclinical development and immunology with clear

🎯 Requirements

• PhD or equivalent degree in Toxicology, Pharmacology, or a related scientific discipline with 9+
• Demonstrated leadership of nonclinical development programs from candidate nomination through
• Subject matter expertise in immunology, supported by hands industry experience and/or immunology
• Broad expertise in pharmaceutical toxicology and working knowledge of discovery toxicology, safety
• Experience integrating nonclinical pharmacology, safety, exposure, biomarker, and clinical data to
• Experience authoring and reviewing nonclinical sections of regulatory submissions; IND experience

🎁 Benefits

• Remote work opportunity within the United States (excluding Alaska and Hawaii)
• Expected travel to Cambridge, MA corporate location several times a year
• Access to work setting enabling meeting all role requirements (privacy, reliable internet, phone