Principal Scientist, Target Discovery & Portfolio Strategy

📋 Description

• Identify promising disease areas; assess unmet needs, disease mechanisms, patient subsets, and
• Find and prioritize targets by combining human genetics, functional genomics, genome-scale
• Assess platform fit with molecular design, protein engineering, and functional screening teams.
• Evaluate causality, desired direction of target modulation, safety risks, and key knowledge gaps.
• Build clear target assessments covering disease rationale, patient selection, competition
• Track emerging science and competition, monitor publications and clinical results.

🎯 Requirements

• PhD in immunology or related field with 6+ years of industry experience in drug discovery, target
• Experience with human genetics, genome-scale multi-omics datasets, human data, cell biology
• Strong scientific judgment to distinguish associations from credible therapeutic opportunities.
• Clear communication skills and ability to guide decisions across disciplines.
• Curiosity, independence, and willingness to challenge assumptions.

🎁 Benefits

• Competitive compensation and benefits package including base salary, bonus, and equity.
• Open, flexible, and friendly work environment.
• Base pay range: $164,000-$205,000 annually (may vary based on market, knowledge, skills, and