Raven StealthCo - Associate Scientist, In Vitro Pharmacology and Assay Development

📋 Description

• Stand up the company's cell culture from the ground up: primary and stem-cell-derived cells
• Design, develop, and run reproducible in vitro assays for oligonucleotides and conjugates
• Build an assay toolkit for deeper hit profiling, including uptake, internalization, and trafficking
• Establish tissue-processing techniques and the ex vivo PD and efficacy analyses supporting in vivo
• Deliver the tissue-exposure and biodistribution data anchoring PK/PD interpretation in
• Develop and implement assays for translational biomarkers that track PD effect, target engagement

🎯 Requirements

• BS with 8+ years or MS with 6+ years of relevant experience, preferably in biotech settings
• Hands-on aseptic technique and mammalian cell culture (immortalized and primary lines) and
• Strong molecular biology and biochemistry: RNA and protein isolation from cells and tissues and
• Experience with oligonucleotide modalities and a range of delivery systems (transfection, free
• Fluency accessing and synthesizing -omics datasets (RNA-seq, spatial transcriptomics, metabolomics
• Some familiarity with histology and in situ tissue analysis, and some coding for larger-dataset

🎁 Benefits

• Potential eligibility for annual bonus and long-term incentives
• Comprehensive benefits package as part of compensation