Senior Scientist I, Analytical Development, Mass Spectrometry tLNP CMC

📋 Description

• Operate, maintain, and troubleshoot mass spectrometry (Orbitrap, TOF) and liquid chromatography
• Document instrument performance, organize regular maintenance, and coordinate with service
• Lead and execute characterization activities to evaluate and elucidate critical quality attributes
• Provide analytical support for cross-functional teams, including formulation development
• Proactively advance LC-MS characterization of biotherapeutics by developing innovative techniques
• Independently conduct sample preparation and LC-MS analyses in compliance with SOPs, and document

🎯 Requirements

• Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field
• Previous experience with mRNA, oligonucleotide, antibody, and LNP analysis by LC-MS is a strong
• Experience in mRNA 5’ capping and 3’ polyA tail LC-MS analysis is preferred.
• Proficient in operating and maintaining mass spectrometry equipment, particularly LC-MS systems
• Experience with LCMS data acquisition and analysis software, such as XCalibur, Protein Metrics
• Organized, detail-oriented, and committed to maintaining proper documentation.

🎁 Benefits

• Comprehensive package of benefits including paid time off (vacation, holidays, sick)
• Eligible to participate in short-term incentive programs.