Senior Scientist I - II, Computational HitGen / LeadGen

📋 Description

• Consult with project team to establish desirable project-relevant hit/lead criteria
• Develop and maintain proficiency with the collection of cutting-edge computational methods
• Support project teams by decisively identifying the method(s) that best fit the project goals, and
• Effectively communicate to the project team the rationale for chosen methodologies, explaining how
• Contribute to development of methods / workflows for computational hit generation, including
• Computational methods to evaluate / optimize synthetic tractability of designs from generative AI

🎯 Requirements

• Degree in relevant field (chemistry / computer science / machine learning / cheminformatics /
• Knowledge and experience in modern computational approaches for medicinal chemistry
• Expertise using cutting-edge computational approaches built on Machine Learning/Deep learning and
• Ability to implement, debug, and maintain computational tools in common programming languages
• Familiarity with AI/ML-enabled molecular generation, pose prediction, affinity prediction and/or
• Familiarity with retrosynthetic analysis, to contribute to refining workflows for

🎁 Benefits

• Comprehensive package of benefits including paid time off (vacation, holidays, sick)
• Medical/dental/vision insurance and 401(k) to eligible employees
• Long-term incentive programs