Senior Scientist II, Recombinant Peptide Process Development

📋 Description

• Lead recombinant peptide process-development activities, including expression strategy, host and
• Design and evaluate expression constructs and microbial hosts, including Escherichia coli and
• Develop and assess fusion-tag and carrier-protein strategies—including His-tag, GST, SUMO, and
• Design and conduct clone-screening studies using microscale cultivation, parallel bioreactors, and
• Develop and optimize peptide recovery processes, including cell harvest and lysis, inclusion-body
• Troubleshoot peptide-specific process challenges, such as aggregation, low solubility, degradation

🎯 Requirements

• PhD with typically 4+ years of relevant experience, master’s degree or equivalent education with
• Thorough theoretical and practical understanding of relevant scientific disciplines, with hands-on
• Demonstrated ability to independently design, execute, and interpret critical experiments to
• Experience developing or optimizing expression processes for peptides, small proteins, or other
• Experience with strain or clone screening, fermentation, and process optimization; familiarity with
• Demonstrated experience with preparative chromatography and peptide or protein purification, as

🎁 Benefits

• Comprehensive package of benefits including paid time off (vacation, holidays, sick)
• This job is eligible to participate in our long-term incentive programs.